Furthermore, the researchers identified FSP1 as the warfarin-insensitive enzyme decreasing vitamin K, the identity of which had been speculated but remained unknown for more than a half-century.
Ferroptosis is a natural type of cell death in which cellular iron plays a major role and is characterized by the oxidative breakdown of cellular membranes. The scientists found that vitamin K in its completely reduced form functions as an antioxidant by efficiently inhibiting ferroptotic cell death. Scientists discover a new function for a long-known molecule.Ī team of researchers from Helmholtz Munich has discovered a new function for vitamin K, which is generally known for its role in blood clotting.
The discovery also suggests that vitamin K treatment might be an effective way to treat ferroptosis-related diseases.
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